Research themes
Adaptation & Natural Selection
Polygenic selection, adaptive introgression, and the interplay between drift and selection (from archaic humans to conservation genomics of tigers).
Population Genomics & Genetic Architecture
Demographic inference, epistasis, and the polygenic basis of complex traits. Statistical methods and software (fastsimcoal2, STRAF). Why most heritability remains missing.
Computational Methods
Machine learning for genomics, simulation-based inference, and AI-assisted research workflows applied to evolutionary and biomedical questions.
Epistemology & Honest Science
Replication crisis, incentive structures in academia, and the role of methodology in producing reliable knowledge. How computational tools can enforce transparency and reproducibility.
Publications
* denotes first or corresponding author
Journal articles
The interaction of biological network topology and mutation effects in complex trait evolution *
in press (2026) in press
Beyond the Cost of Complexity: Gene-Intrinsic versus Topological Constraint in Regulatory Networks *
submitted (2026) submitted
Dual-kingdom necrobiome succession extends postmortem interval estimation into skeletonization
Forensic Science International: Genetics
STRAF 2: New features and improvements of the STR population data analysis software *
Forensic Science International: Genetics
Genomes of Microtus rodents highlight the importance of olfactory and immune systems in their fast radiation *
Genome Biology and Evolution
A holistic approach for the selection of forensic DNA swabs
Forensic Science International
Human background DNA on stones in an urban environment
Forensic Science International: Genetics
Population genetic analysis of 12 X-chromosomal STRs in a Swiss sample
International Journal of Legal Medicine
Recent evolutionary history of tigers highlights contrasting roles of genetic drift and selection
Molecular Biology and Evolution
Expanding the Swiss autosomal marker set to 32 STRs
International Journal of Legal Medicine
Polygenic patterns of adaptive introgression in modern humans are mainly shaped by response to pathogens *
Molecular Biology and Evolution
STRAF—a convenient online tool for STR data evaluation in forensic genetics *
Forensic Science International: Genetics
Detecting gene subnetworks under selection in biological pathways *
Nucleic Acids Research
The summary-likelihood method and its implementation in the Infusion package
Molecular Ecology Resources
The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases
Nucleic Acids Research
Book chapters
Nothing Stands Still in the Streams of Life *
The Art of Theoretical Biology
PhD thesis
Detection of polygenic selection from genomic data: new insights into adaptation, introgression and speciation
University of Bern, Switzerland — summa cum laude
Statistical methods for detecting selection in large-scale genomic datasets, with applications to human evolution and adaptation. Supervisor: Prof. Laurent Excoffier.
Software & methods
STRAF
Lead DeveloperOnline tool for STR data evaluation in forensic genetics.
signet
Lead DeveloperR package for detection of gene subnetworks under selection in biological pathways.
Tercen Operators
Lead DeveloperSuite of bioinformatics operators for flow cytometry, scRNA-seq, and multi-omics analysis.
Co-introgression Test
Lead DeveloperStatistical method for detecting coordinated adaptive introgression across gene networks in human populations.
RNDsp
Lead DeveloperMethod for estimating species-specific relative node depth to detect lineage-specific selection in multi-species comparisons.
CV
Experience
Founder & Owner
AlgoLife SARL (formerly Gouy Data Consulting), France/Switzerland
Data science and software development for life sciences companies, universities, and local governments.
Selected projects:
- Head of Bioinformatics, Tercen (2022–2025) - Led bioinformatics and AI product development for a cloud-based multi-omics analysis platform. MCP server for automated data analysis selected for SLAS 2026 Innovation AveNEW.
- Mitan - Geospatial forest monitoring platform combining remote sensing, ecology, and local knowledge. Deployed with NGOs and French communes. aumitan.com
- Predictive algorithm for IVF success rates, in collaboration with a health-tech startup and a major university hospital in Paris (AP-HP).
Senior Expert Data Science II
Novartis Pharma AG (via Brine SA), Basel, Switzerland
Contributed to Novartis's data42 initiative, applying AI and large-scale real-world data to drug discovery and development. Developed ML models on a large pharmaceutical dataset and contributed to the Map of Life platform for disease-gene-drug network analysis.
Scientific Collaborator
University of Bern, Institute of Forensic Medicine
Statistical analysis of experimental data and forensic software development (STRAF 2). Two publications in forensic genetics.
PhD Candidate
University of Bern, Switzerland
Developed statistical and ML algorithms (Python, R, C++) for large-scale genomic datasets. 180 hours of teaching (Genomics, Statistics, R). Thesis defended summa cum laude.
Research Internships
University of Montpellier & CNRS Moulis, France
Three internships focused on genomics, scientific software development (C++), and molecular biology.
Computer Science Tutor
University of Limoges, France
Trained students for IT certificates (350 hours) and managed SQL databases.
Education
PhD in Ecology and Evolution (Genomics)
University of Bern, Switzerland — summa cum laude
Thesis: "Detection of polygenic selection from genomic data: new insights into adaptation, introgression and speciation"
Supervisor: Prof. Laurent Excoffier (SIB Swiss Institute of Bioinformatics)
Master's in Evolutionary Biology & Ecology
University of Montpellier, France — Highest honors
Specialization: Population genomics and mathematical modeling
Supervisors: François Rousset & Pierrick Labbé
Bachelor's in Population Biology
University of Limoges, France — High honors
Teaching & supervision
University teaching
- University of Bern (2015–2019) — 180h total: Genomics and Bioinformatics (Master's), Statistics for Biologists, Introduction to R, Population Genetics Seminars
- University of Limoges (2012–2013) — 350h: IT certification training, database management (SQL)
Student supervision
- Engineering internship (2025) — AI automation of data analysis workflows
- Master's thesis (2019) — University of Bern, co-supervisor
- Master's thesis (2018) — ML methods in population genetics, University of Bern